Authors struggle In certain bioassay techniques on controversial TOFT theory of cancer Versus SMT Model

Writing in certain bioassay techniques and cancer scientists Ana Soto, Carlos Sonnenschein pit their controversial tissue Organization (TOFT) Field Theory of the origin of cancer against the generally accepted theory for somatic Mutation (SMT) in what is considered the first time that the two theories have formally against each other-defended by authors from opposite sides of the debate-in a common Forum for discussion.

Soto and Sonnenschein, at Tufts University, claim that SMT, which is based on the accumulation of genetic mutations in cells, not not only an explanation of observable phenomena in biology of the cancer, but with the current technologies essentially untestable.

The TOFT theory States that cancer is a disease clones, cell-based and implicitly assumes that the default state of immobility cells in multicellular organisms.

Dr. David Vaux, writes "SMT is strongly supported by observations of leukemias that specific chromosomal translocations," from La Trobe Institute for Molecular Science, Australia, in defense of SMT. "perhaps the strongest validation comes from the successful treatment of certain malignancies with drugs which have as their direct objective the product of the mutant gene."

"This proves to be the first time that the TOFT is formally gone head-to-head with the SMT in a common arena" said certain bioassay techniques, editor-in-Chief Andrew Moore.

"Certain bioassay techniques is of the opinion that science advances through the clear presentation of opposing views, and a new forum for lively debate that focuses on the fundamental basis of cancer: can our readers decide for themselves!" adds David Thomas, Certain bioassay techniques, Editorial Board Member, and co-editor of the Point Counter point pair.

Source:
Ben Norman
Wiley-Blackwell